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CS-W001157 4
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1-Formyl-beta-carboline

  • CAS No. 20127-63-3

  • Cat. No. CS-0196964
  • Purity≥98%
  • MDL No.MFCD14706724

*For research and further manufacturing use only, not for direct human use.

1-Formyl-beta-carboline|CS-0196964

Structure of 20127-63-3

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General Information

  • CAS No. 20127-63-3
  • Cat. No. CS-0196964
  • Purity ≥98%
  • MDL No. MFCD14706724
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₈N₂O
  • Molecular Weight 196.20
  • Synonym(s) None
  • SMILES C1=CC=C2C(=C1)C3=C(C(=NC=C3)C=O)N2

Description

1-Formyl-beta-carboline is a heterocyclic compound featuring a formyl group at the 1-position of the beta-carboline core. This moiety enhances reactivity in C–H functionalization and conjugate addition processes, enabling efficient integration into complex molecular architectures. The electron-deficient formyl group facilitates nucleophilic attack and serves as a handle for further derivatization under mild conditions.

Application

1-Formyl-beta-carboline serves as a versatile heterocyclic building block for the synthesis of biologically relevant beta-carboline derivatives. The formyl group enables direct functionalization via nucleophilic additions, condensations, and reductive amination, facilitating rapid diversification of the core scaffold. Its bench-stable nature and compatibility with standard synthetic protocols make it well-suited for medicinal chemistry campaigns targeting CNS-active compounds and kinase inhibitors.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   45.75
  • LogP   2.5286
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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