Fmoc-Orn(Fmoc)-OH

Name: Fmoc-Orn(Fmoc)-OH
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 201046-59-5
Cat. No. CS-0149830
Purity≥98%
MDL No.MFCD00153362

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Description

Fmoc-Orn(Fmoc)-OH is a doubly protected ornithine derivative featuring two Fmoc groups, enabling efficient incorporation into solid-phase peptide synthesis. The bis-Fmoc protection ensures orthogonal deprotection and minimizes side reactions during chain elongation. This stable, bench-ready reagent simplifies the installation of ornithine residues with high fidelity.

Application

Fmoc-Orn(Fmoc)-OH serves as a bifunctional amino acid building block for solid-phase peptide synthesis, enabling the introduction of ornithine residues with orthogonal protection. The Fmoc group on the α-amino function ensures compatibility with base-labile deprotection, while the second Fmoc moiety on the side-chain amine allows selective activation and coupling under standard conditions. Its stability under routine handling and ease of purification facilitate efficient incorporation into peptide sequences requiring arginine-like functionality or cyclic scaffold construction.

General Information

CAS No. 201046-59-5
Cat. No. CS-0149830
Purity ≥98%
MDL No. MFCD00153362
Storage Store at room temperature, keep dry and cool
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₃₅H₃₂N₂O₆
Molecular Weight 576.64
Synonym(s) None
SMILES O=C(O)[C@@H](NC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)CCCNC(OCC4C5=CC=CC=C5C6=CC=CC=C64)=O

Computational Chemistry Data

TPSA 113.96
LogP 6.2972
H_Acceptors 5
H_Donors 3
Rotatable_Bonds 10

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Other Classifications

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Life Science Amino Acids and their Derivatives Non-protein amino acids

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Unnatural Amino Acid Derivatives

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Fmoc-Orn(Fmoc)-OH

CAS No. 201046-59-5

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