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CS-W001157 4
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(6-Methoxy-1H-benzo[d]imidazol-2-yl)methanol

  • CAS No. 20033-99-2

  • Cat. No. CS-0135309
  • Purity≥97%
  • MDL No.MFCD08059827
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

(6-Methoxy-1H-benzo[d]imidazol-2-yl)methanol|CS-0135309

Structure of 20033-99-2

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Description

This bench-stable benzimidazole derivative features a methoxy group at the 6-position and a primary alcohol at the 2-position, enabling direct functionalization in synthetic workflows. The electron-rich aromatic core supports efficient coupling reactions, while the hydroxymethyl moiety offers versatility in conjugation strategies.

Application

(6-Methoxy-1H-benzo[d]imidazol-2-yl)methanol serves as a versatile building block for heterocyclic synthesis, enabling efficient functionalization at the benzoimidazole C2 position. Its aldehyde functionality facilitates reductive amination, coupling reactions, and conjugation with nucleophiles, while the methoxy group enhances solubility and modulates electronic properties. The compound exhibits good bench stability and is compatible with standard purification protocols, making it well-suited for medicinal chemistry campaigns and API intermediate development.

General Information

  • CAS No. 20033-99-2
  • Cat. No. CS-0135309
  • Purity ≥97%
  • MDL No. MFCD08059827
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₀N₂O₂
  • Molecular Weight 178.19
  • Synonym(s) 2-(Hydroxymethyl)-5-methoxybenzimidazole
  • SMILES COC1=CC=C2C(N=C(CO)N2)=C1

Computational Chemistry Data

  • TPSA   58.14
  • LogP   1.0638
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

Safety Information

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GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H318
Precautionary Statements : P280-P305+P351+P338-P310

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