2-Bromo-1-(4-iodophenyl)ethanone

Name: 2-Bromo-1-(4-iodophenyl)ethanone
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 31827-94-8
Cat. No. CS-0186567
Purity≥97%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-Bromo-1-(4-iodophenyl)ethanone|CS-0186567

Structure of 31827-94-8

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 31827-94-8
Cat. No. CS-0186567
Purity ≥97%
MDL No. None
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₆BrIO
Molecular Weight 324.94
Synonym(s) 4-IODOPHENACYL BROMIDE
SMILES C1=C(C=CC(=C1)I)C(=O)CBr

Description

2-Bromo-1-(4-iodophenyl)ethanone is a halogenated aryl ketone featuring both bromo and iodo substituents on an ethanone scaffold. This dual-halogenation enables direct participation in cross-coupling reactions, particularly Suzuki-Miyaura and Stille transformations. The molecule exhibits high stability under standard bench conditions and facilitates efficient functionalization of aromatic systems.

Application

2-Bromo-1-(4-iodophenyl)ethanone serves as a versatile aryl ketone building block for palladium-catalyzed cross-coupling reactions. The bromo and iodo substituents enable sequential functionalization via Suzuki, Stille, or Negishi coupling protocols. Its bench-stable nature and compatibility with standard reaction conditions facilitate efficient construction of biaryl scaffolds and complex heterocycles in medicinal chemistry and materials synthesis.

Synthesis

Route1
- In-stock
  
  13329-40-3
- ~99%
- In-stock
  
  31827-94-8
References
- CYTOKINETICS, INC. Patent: WO2007/56056 A2, 2007 ; Location in patent: Page/Page column 60; 69 ;
Route2
- 186581-53-3
- In-stock
  
  619-58-9
- ~94%
- In-stock
  
  31827-94-8
References
- Richards, Justin J.; Melander, Christian Journal of Organic Chemistry, 2008 , vol. 73, # 13 p. 5191 - 5193
Route3
- In-stock
  
  13329-40-3
- ~71%
- 556110-57-7
- In-stock
  
  31827-94-8
References
- Roman, Gheorghe; Vlahakis, Jason Z.; Vukomanovic, Dragic; Nakatsu, Kanji; Szarek, Walter A. ChemMedChem, 2010 , vol. 5, # 9 p. 1541 - 1555

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H319
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 17.07
LogP 2.8688
H_Acceptors 1
H_Donors 0
Rotatable_Bonds 2

Other Classifications

Building Blocks Functional Group Ketone

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

2-Bromo-1-(4-iodophenyl)ethanone sigma2-Bromo-1-(4-iodophenyl)ethanone manufacturer2-Bromo-1-(4-iodophenyl)ethanone price2-Bromo-1-(4-iodophenyl)ethanone structure2-Bromo-1-(4-iodophenyl)ethanone SDSbuy 2-Bromo-1-(4-iodophenyl)ethanone2-Bromo-1-(4-iodophenyl)ethanone supplier2-Bromo-1-(4-iodophenyl)ethanone uses2-Bromo-1-(4-iodophenyl)ethanone molecular weightprice of 2-Bromo-1-(4-iodophenyl)ethanone2-Bromo-1-(4-iodophenyl)ethanone chemical name formula of 2-Bromo-1-(4-iodophenyl)ethanone

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

2-Bromo-1-(4-iodophenyl)ethanone

CAS No. 31827-94-8

Recommended Products

General Information

Description

Application

Synthesis

References

References

References

Safety Information

Quality Control

Computational Chemistry Data

Similar Products

Other Classifications

Recently Viewed Products

Key Words