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Structure of 199526-98-2
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4,6-Difluoro-2,3-dihydro-1H-indole delivers a fluorinated indoline scaffold with enhanced electronic modulation and metabolic stability. The ortho-fluorine substituents at positions 4 and 6 influence reactivity and conformational rigidity, enabling efficient incorporation into bioactive molecules. This bench-stable, moisture-tolerant heterocycle serves as a key intermediate in medicinal chemistry campaigns targeting CNS agents and kinase inhibitors.
4,6-Difluoro-2,3-dihydro-1H-indole serves as a valuable building block in medicinal chemistry, enabling the construction of fluorinated heterocyclic scaffolds with enhanced metabolic stability. Its difluorinated aromatic core facilitates selective functionalization and improves lipophilicity profiles. The compound exhibits good bench stability and compatibility with standard coupling reactions, making it well-suited for modular synthesis of bioactive molecules.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: