N-[3,5-Bis(trifluoromethyl)phenyl]-N'-[(1R,2R)-2-[(11bS)-3,5-dihydro-4H-dinaphth[2,1-c:1',2'-e]azepin-4-yl]cyclohexyl]thiourea

Name: N-[3,5-Bis(trifluoromethyl)phenyl]-N'-[(1R,2R)-2-[(11bS)-3,5-dihydro-4H-dinaphth[2,1-c:1',2'-e]azepin-4-yl]cyclohexyl]thiourea
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1984862-45-4
Cat. No. CS-0090855
Purity≥97%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

N-[3,5-Bis(trifluoromethyl)phenyl]-N'-[(1R,2R)-2-[(11bS)-3,5-dihydro-4H-dinaphth[2,1-c:1',2'-e]azepin-4-yl]cyclohexyl]thiourea|CS-0090855

Structure of 1984862-45-4

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 1984862-45-4
Cat. No. CS-0090855
Purity ≥97%
MDL No. None
Storage 4°C, protect from light, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₃₇H₃₁F₆N₃S
Molecular Weight 663.72
Synonym(s) None
SMILES S=C(NC1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1)N[C@H](CCCC2)[C@@H]2N(C3)CC4=CC=C5C(C=CC=C5)=[C@]4[C@]6=C3C=CC7=CC=CC=C76

Description

N-[3,5-Bis(trifluoromethyl)phenyl]-N'-[(1R,2R)-2-[(11bS)-3,5-dihydro-4H-dinaphth[2,1-c:1',2'-e]azepin-4-yl]cyclohexyl]thiourea features a sterically hindered thiourea core flanked by electron-deficient aryl and complex polycyclic substituents. This configuration imparts enhanced binding affinity and metabolic stability, enabling its use in targeted small-molecule screening campaigns requiring high selectivity and solubility under physiological conditions.

Application

N-[3,5-Bis(trifluoromethyl)phenyl]-N'-[(1R,2R)-2-[(11bS)-3,5-dihydro-4H-dinaphth[2,1-c:1',2'-e]azepin-4-yl]cyclohexyl]thiourea serves as a structurally complex, bench-stable thiourea derivative enabling targeted functionalization in medicinal chemistry campaigns. Its trifluoromethylated aryl group enhances metabolic stability and lipophilicity, while the fused dinaphthazepine core provides a rigid, three-dimensional scaffold suitable for probing protein-ligand interactions. The thiourea moiety facilitates hydrogen bonding in target engagement and supports purification via crystallization or chromatography. Functions effectively in standard coupling protocols and demonstrates compatibility with diverse reaction conditions.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 27.3
LogP 10.311
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 3

Key Words

1984862-45-4 sigma1984862-45-4 manufacturer1984862-45-4 price1984862-45-4 structure1984862-45-4 SDSbuy 1984862-45-41984862-45-4 supplier1984862-45-4 uses1984862-45-4 molecular weightprice of 1984862-45-41984862-45-4 chemical name formula of 1984862-45-4

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

N-[3,5-Bis(trifluoromethyl)phenyl]-N'-[(1R,2R)-2-[(11bS)-3,5-dihydro-4H-dinaphth[2,1-c:1',2'-e]azepin-4-yl]cyclohexyl]thiourea

CAS No. 1984862-45-4

Recommended Products