N-[(1S,2S)-2-Aminocyclohexyl]-N'-[3,5-bis(trifluoromethyl)phenyl]thiourea

Name: N-[(1S,2S)-2-Aminocyclohexyl]-N'-[3,5-bis(trifluoromethyl)phenyl]thiourea
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1027476-96-5
Cat. No. CS-0092771
Purity≥95%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

N-[(1S,2S)-2-Aminocyclohexyl]-N'-[3,5-bis(trifluoromethyl)phenyl]thiourea|CS-0092771

Structure of 1027476-96-5

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 1027476-96-5
Cat. No. CS-0092771
Purity ≥95%
MDL No. None
Storage 4°C, protect from light, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₅H₁₇F₆N₃S
Molecular Weight 385.37
Synonym(s) N-[(1S,2S)-2-aMinocyclohexyl]-N'-[3,5-bis(trifluoroMethyl)phenyl]-Thiourea
SMILES S=C(NC1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1)N[C@H]2CCCC[C@@H]2N

Description

N-[(1S,2S)-2-Aminocyclohexyl]-N'-[3,5-bis(trifluoromethyl)phenyl]thiourea features a chiral cyclohexylamine scaffold paired with a highly electron-deficient aryl thiourea moiety. This combination enables robust coordination in asymmetric catalysis and provides enhanced stability under oxidative conditions. The trifluoromethyl groups confer strong lipophilicity and resistance to metabolic degradation.

Application

N-[(1S,2S)-2-Aminocyclohexyl]-N'-[3,5-bis(trifluoromethyl)phenyl]thiourea serves as a versatile bifunctional building block in medicinal chemistry, enabling efficient construction of heterocyclic scaffolds via cyclization reactions. The thiourea moiety facilitates hydrogen bonding and enhances solubility, while the sterically defined cyclohexyl amine and electron-deficient aryl groups provide robust functional group tolerance. Its bench-stable crystalline form simplifies handling and purification in multi-step synthesis workflows.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H413
Precautionary Statements : P264-P270-P330

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 50.08
LogP 4.2805
H_Acceptors 2
H_Donors 3
Rotatable_Bonds 2

Key Words

1027476-96-5 sigma1027476-96-5 manufacturer1027476-96-5 price1027476-96-5 structure1027476-96-5 SDSbuy 1027476-96-51027476-96-5 supplier1027476-96-5 uses1027476-96-5 molecular weightprice of 1027476-96-51027476-96-5 chemical name formula of 1027476-96-5

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

N-[(1S,2S)-2-Aminocyclohexyl]-N'-[3,5-bis(trifluoromethyl)phenyl]thiourea

CAS No. 1027476-96-5

Recommended Products