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CS-W001157 4
Total: USD 88.00

2-(o-Tolyl)ethanol

  • CAS No. 19819-98-8

  • Cat. No. CS-W021450
  • Purity≥96%
  • MDL No.MFCD00044241

*For research and further manufacturing use only, not for direct human use.

2-(o-Tolyl)ethanol|CS-W021450

Structure of 19819-98-8

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General Information

  • CAS No. 19819-98-8
  • Cat. No. CS-W021450
  • Purity ≥96%
  • MDL No. MFCD00044241
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₂O
  • Molecular Weight 136.19
  • Synonym(s) 2-o-tolylethanol
  • SMILES CC1=CC=CC=C1CCO

Description

2-(o-Tolyl)ethanol features a benzyl ether linkage with an ortho-methyl substituent, offering enhanced lipophilicity and metabolic stability. This bench-stable compound integrates readily into pharmaceutical intermediates and serves as a key scaffold in bioactive molecule design.

Application

2-(o-Tolyl)ethanol serves as a versatile building block in medicinal chemistry and materials synthesis, enabling efficient construction of bioactive scaffolds and functional polymers. Its benzylic alcohol functionality offers high reactivity in oxidation, protection, and coupling reactions, while the ortho-methyl group enhances metabolic stability and modulates lipophilicity. Bench-stable and readily purified by distillation or recrystallization, it functions effectively in standard synthetic workflows.

Synthesis

  • Route1

    References

    • Chemistry - A European Journal, , vol. 5, # 4 p. 1320 - 1330
  • Route2

    References

    • Dong, Guangbin; Teo, Peili; Wickens, Zachary K.; Grubbs, Robert H. Science, 2011 , vol. 333, # 6049 p. 1609 - 1612
  • Route3
    • null|null
      88041-87-6
    • ~58%
    • In-stock
      2-(o-Tolyl)ethanol|CS-W021450
      19819-98-8

    References

    • Gomez, Cecilia; Macia, Beatriz; Lillo, Victor J.; Yus, Miguel Tetrahedron, 2006 , vol. 62, # 42 p. 9832 - 9839

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   20.23
  • LogP   1.52982
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   2

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