Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

1,6-Naphthyridine-2-carboxylic acid

  • CAS No. 197507-59-8

  • Cat. No. CS-D0176
  • Purity≥98%
  • MDL No.MFCD00202908

*For research and further manufacturing use only, not for direct human use.

1,6-Naphthyridine-2-carboxylic acid|CS-D0176

Structure of 197507-59-8

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 197507-59-8
  • Cat. No. CS-D0176
  • Purity ≥98%
  • MDL No. MFCD00202908
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₆N₂O₂
  • Molecular Weight None
  • Synonym(s) 2-Carboxy-1,6-naphthyridine
  • SMILES O=C(C1=NC2=CC=NC=C2C=C1)O

Description

1,6-Naphthyridine-2-carboxylic acid features a rigid, electron-deficient heteroaromatic core paired with a carboxylic acid functional group, enabling direct conjugation in medicinal chemistry scaffolds. This bench-stable compound integrates readily into bioactive molecules, offering enhanced solubility and binding versatility in target-directed design.

Application

1,6-Naphthyridine-2-carboxylic acid serves as a versatile scaffold for medicinal chemistry and heterocyclic synthesis, enabling efficient construction of biologically relevant frameworks. Its carboxylic acid functionality facilitates direct amidation, esterification, and coupling reactions, while the fused bicyclic core offers enhanced metabolic stability and defined molecular geometry. The compound exhibits good bench stability and is readily purified by recrystallization, making it well-suited for iterative synthetic campaigns in drug discovery.

Synthesis

  • Route1

    References

    • Chan, Laval; Jin, Haolun; Stefanac, Tomislav; Lavallee, Jean-Francois; Falardeau, Guy; Wang, Wei; Bedard, Jean; May, Suzanne; Yuen, Leonard Journal of Medicinal Chemistry, 1999 , vol. 42, # 16 p. 3023 - 3025
  • Route2

    References

    • Journal of Medicinal Chemistry, , vol. 42, # 16 p. 3023 - 3025
  • Route3

    References

    • Journal of Medicinal Chemistry, , vol. 42, # 16 p. 3023 - 3025

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H319
Precautionary Statements : P264-P280-P305+P351+P338-P337+P313

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   63.08
  • LogP   1.328
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1,6-Naphthyridine-2-carboxylic acid sigma1,6-Naphthyridine-2-carboxylic acid manufacturer1,6-Naphthyridine-2-carboxylic acid price1,6-Naphthyridine-2-carboxylic acid structure1,6-Naphthyridine-2-carboxylic acid SDSbuy 1,6-Naphthyridine-2-carboxylic acid1,6-Naphthyridine-2-carboxylic acid supplier1,6-Naphthyridine-2-carboxylic acid uses1,6-Naphthyridine-2-carboxylic acid molecular weightprice of 1,6-Naphthyridine-2-carboxylic acid1,6-Naphthyridine-2-carboxylic acid chemical name formula of 1,6-Naphthyridine-2-carboxylic acid
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label