1H-Pyrrolo[3,2-b]pyridine-3-carboxylic acid

Name: 1H-Pyrrolo[3,2-b]pyridine-3-carboxylic acid
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 860496-20-4
Cat. No. CS-W019708
Purity≥97%
MDL No.MFCD11559014

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

1H-Pyrrolo[3,2-b]pyridine-3-carboxylic acid|CS-W019708

Structure of 860496-20-4

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 860496-20-4
Cat. No. CS-W019708
Purity ≥97%
MDL No. MFCD11559014
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₆N₂O₂
Molecular Weight 162.15
Synonym(s) None
SMILES O=C(C1=CNC2=CC=CN=C21)O

Description

1H-Pyrrolo[3,2-b]pyridine-3-carboxylic acid features a fused heterocyclic core with a carboxylic acid group at the 3-position, enabling direct conjugation or derivatization in synthetic routes. The electron-deficient pyrrolopyridine scaffold enhances reactivity in cross-coupling and cyclization processes, while the acidic proton supports salt formation for improved solubility and handling. This structure serves as a key intermediate in medicinal chemistry campaigns targeting kinase inhibitors and CNS-active compounds.

Application

1H-Pyrrolo[3,2-b]pyridine-3-carboxylic acid serves as a versatile heterocyclic building block for medicinal chemistry and materials science. Its rigid fused scaffold enables predictable bioactive conformation and facilitates functionalization at the carboxylic acid terminus. The molecule exhibits good bench stability, moderate solubility in common organic solvents, and compatibility with standard coupling reactions, including amide formation and esterification, supporting efficient access to diverse analogs in lead optimization campaigns.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 65.98
LogP 1.2611
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 1

Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyrrole compounds

Key Words

860496-20-4 sigma860496-20-4 manufacturer860496-20-4 price860496-20-4 structure860496-20-4 SDSbuy 860496-20-4860496-20-4 supplier860496-20-4 uses860496-20-4 molecular weightprice of 860496-20-4860496-20-4 chemical name formula of 860496-20-4

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

1H-Pyrrolo[3,2-b]pyridine-3-carboxylic acid

CAS No. 860496-20-4

Recommended Products