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CS-W001157 4
Total: USD 88.00

5-(Aminomethyl)nicotinamide dihydrochloride

  • CAS No. 1956365-61-9

  • Cat. No. CS-0197736
  • Purity≥98%
  • MDL No.MFCD28144952

*For research and further manufacturing use only, not for direct human use.

5-(Aminomethyl)nicotinamide dihydrochloride|CS-0197736

Structure of 1956365-61-9

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General Information

  • CAS No. 1956365-61-9
  • Cat. No. CS-0197736
  • Purity ≥98%
  • MDL No. MFCD28144952
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₁Cl₂N₃O
  • Molecular Weight 224.09
  • Synonym(s) None
  • SMILES O=C(N)C1=CN=CC(CN)=C1.Cl.Cl

Description

5-(Aminomethyl)nicotinamide hydrochloride delivers a reactive aliphatic amine handle at the pyridine ring's 5-position, enabling site-specific conjugation in bioconjugation workflows. This bench-stable, moisture-tolerant derivative integrates readily into peptide and protein labeling strategies, offering enhanced solubility and compatibility with aqueous reaction conditions.

Application

5-(Aminomethyl)nicotinamide hydrochloride serves as a versatile building block for nicotinamide-derived scaffolds, enabling direct incorporation into bioactive molecules through amide coupling or reductive amination. Its terminal primary amine and carboxamide functionality offer orthogonal reactivity for conjugation strategies, while the hydrochloride salt ensures excellent solubility and bench stability in aqueous and polar organic media.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   82
  • LogP   0.061
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

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