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CS-W001157 4
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β-Glutamic acid

  • CAS No. 1948-48-7

  • Cat. No. CS-0161137
  • Purity≥95%
  • MDL No.MFCD00056698

*For research and further manufacturing use only, not for direct human use.

β-Glutamic acid|CS-0161137

Structure of 1948-48-7

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General Information

  • CAS No. 1948-48-7
  • Cat. No. CS-0161137
  • Purity ≥95%
  • MDL No. MFCD00056698
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₉NO₄
  • Molecular Weight 147.13
  • Synonym(s) 3-Aminopentanedioic acid
  • SMILES O=C(O)CC(N)CC(O)=O

Description

β-Glutamic acid features a γ-carboxyl group positioned two atoms away from the α-amino nitrogen, enabling unique coordination in metal-binding systems and facilitating incorporation into bioactive peptides. This structural arrangement supports applications in chelation chemistry and peptide synthesis where side-chain functionality is critical.

Application

β-Glutamic acid serves as a key building block for the synthesis of γ-amino acids, peptidomimetics, and bioactive heterocycles. Its bifunctional nature—carboxylic acid and amine groups separated by two methylene units—enables straightforward incorporation into peptide backbones and facilitates ring formation under standard conditions. The compound exhibits good bench stability and is compatible with common protecting group strategies, making it well-suited for iterative synthetic sequences in medicinal chemistry and process development.

Synthesis

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    • In-stock
      β-Glutamic acid|CS-0161137
      1948-48-7

    References

    • Khimicheskaya Nauka i Promyshlennost, , vol. 2, p. 136 Chem.Abstr., , p. 6183 Journal of the American Chemical Society, , vol. 77, p. 5427
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    • In-stock
      β-Glutamic acid|CS-0161137
      1948-48-7

    References

    • Journal of the American Chemical Society, , vol. 83, p. 1093 - 1096
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    • In-stock
      β-Glutamic acid|CS-0161137
      1948-48-7

    References

    • Journal of the American Chemical Society, , vol. 77, p. 5427

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   100.62
  • LogP   -0.7369
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   4

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