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CS-W001157 4
Total: USD 88.00

1-Stearoyl-sn-glycero-3-phosphocholine

  • CAS No. 19420-57-6

  • Cat. No. CS-0099291
  • Purity≥98%
  • MDL No.MFCD00050427

*For research and further manufacturing use only, not for direct human use.

1-Stearoyl-sn-glycero-3-phosphocholine|CS-0099291

Structure of 19420-57-6

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General Information

  • CAS No. 19420-57-6
  • Cat. No. CS-0099291
  • Purity ≥98%
  • MDL No. MFCD00050427
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₆H₅₄NO₇P
  • Molecular Weight 523.68
  • Synonym(s) 18:0 Lyso-PC; LPC(18:0)
  • SMILES CCCCCCCCCCCCCCCCCC(OC[C@@H](O)COP(OCC[N+](C)(C)C)([O-])=O)=O

Description

1-Stearoyl-sn-glycero-3-phosphocholine is a zwitterionic phospholipid featuring a saturated stearoyl chain at the sn-1 position and a phosphorylcholine headgroup. This structure imparts excellent membrane mimicry, stability under physiological conditions, and compatibility with liposomal formulations for drug delivery and biomimetic studies.

Application

1-Stearoyl-sn-glycero-3-phosphocholine (CAS 19420-57-6) prevents oxidative lipid and protein modifications in cellular membranes by stabilizing phospholipid bilayers under stress conditions. This enhances membrane integrity. Researchers use it to model lipid raft dynamics and refine liposomal drug delivery systems with improved stability and targeted release profiles.

Synthesis

  • Route1
    • In-stock
      sn-Glycero-3-phosphocholine|CS-2195
      28319-77-9
    • null|null
      112-76-5
    • ~95%
    • In-stock
      1-Stearoyl-sn-glycero-3-phosphocholine|CS-0099291
      19420-57-6

    References

    • Organic and Biomolecular Chemistry, , vol. 4, # 15 p. 2974 - 2978
  • Route2

    References

    • Journal of Materials Chemistry, , vol. 10, # 5 p. 1047 - 1059
  • Route3
    • null|null
      171597-35-6
    • ~%
    • In-stock
      1-Stearoyl-sn-glycero-3-phosphocholine|CS-0099291
      19420-57-6

    References

    • Journal of the Chemical Society, Chemical Communications, , # 18 p. 1281 - 1282 Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 31, # 12 p. 824 - 827

Safety Information

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GHS Pictogram : N/A
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Signal Word : N/A
UN#: N/A
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Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

Quality Control

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Computational Chemistry Data

  • TPSA   105.12
  • LogP   5.3598
  • H_Acceptors   7
  • H_Donors   1
  • Rotatable_Bonds   25

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