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CS-W001157 4
Total: USD 88.00

1,5-Anhydrosorbitol

  • CAS No. 154-58-5

  • Cat. No. CS-0059497
  • Molecule weight164.16
  • Purity≥97%
  • MDL No.MFCD00067386

*For research and further manufacturing use only, not for direct human use.

1,5-Anhydrosorbitol|CS-0059497

Structure of 154-58-5

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General Information

  • CAS No. 154-58-5
  • Cat. No. CS-0059497
  • Purity ≥97%
  • MDL No. MFCD00067386
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₂O₅
  • Molecular Weight 164.16
  • Synonym(s) 1,5-Anhydro-D-glucitol
  • SMILES OC[C@@H]1[C@@H](O)[C@H](O)[C@H](CO1)O

Description

1,5-Anhydrosorbitol offers a rigid, cyclic backbone with strategically positioned hydroxyl groups, enabling precise functionalization in carbohydrate chemistry. This stable scaffold serves as a key intermediate for glycosylation studies and bioconjugation workflows, providing consistent reactivity under standard conditions.

Synthesis

  • Route1
    • (2R,3R,4R,5S)-2-(Acetoxymethyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate|CS-0941105
      13137-69-4
    • ~96%
    • In-stock
      1,5-Anhydrosorbitol|CS-0059497
      154-58-5

    References

    • Bioorganic and Medicinal Chemistry, , vol. 14, # 19 p. 6659 - 6665
  • Route2
    • null|null
      1338660-78-8
    • ~98%
    • In-stock
      1,5-Anhydrosorbitol|CS-0059497
      154-58-5

    References

    • Tetrahedron Letters, , vol. 52, # 42 p. 5421 - 5423
  • Route3
    • 1,5-Anhydro-D-fructose|CS-0794365
      75414-43-6
    • ~60%
    • 1,5-Anhydro-D-mannitol|CS-0204027
      492-93-3
    • In-stock
      1,5-Anhydrosorbitol|CS-0059497
      154-58-5

    References

    • Journal of Carbohydrate Chemistry, , vol. 19, # 6 p. 717 - 725

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   90.15
  • LogP   -2.5398
  • H_Acceptors   5
  • H_Donors   4
  • Rotatable_Bonds   1

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