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Structure of 1936049-54-5
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Methyl 2-bromo-5-(trifluoromethyl)thiazole-4-carboxylate is a bench-stable, moisture-tolerant heterocyclic building block featuring a bromine atom at the 2-position and a trifluoromethyl group at the 5-position. This combination enables efficient cross-coupling reactions and facilitates incorporation into bioactive molecules through palladium-catalyzed transformations. The methyl ester functionality supports further derivatization under standard conditions.
Methyl 2-bromo-5-(trifluoromethyl)thiazole-4-carboxylate serves as a versatile building block for constructing biologically relevant thiazole scaffolds. Its bromine and trifluoromethyl groups enable palladium-catalyzed cross-coupling reactions and enhance metabolic stability. The ester functionality facilitates downstream derivatization, while the molecule exhibits excellent bench stability and compatibility with standard synthetic workflows.
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H311-H331
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P405-P501
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Lot numbers can be found on the outside label of a product: