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CS-W001157 4
Total: USD 88.00

4-Chloropyridine-2-carbonitrile

  • CAS No. 19235-89-3

  • Cat. No. CS-W008318
  • Purity≥98%
  • MDL No.MFCD06009833

*For research and further manufacturing use only, not for direct human use.

4-Chloropyridine-2-carbonitrile|CS-W008318

Structure of 19235-89-3

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General Information

  • CAS No. 19235-89-3
  • Cat. No. CS-W008318
  • Purity ≥98%
  • MDL No. MFCD06009833
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₃ClN₂
  • Molecular Weight 138.55
  • Synonym(s) IFLAB-BB F3099-7226
  • SMILES C1=C(Cl)C=CN=C1C#N

Description

4-Chloropyridine-2-carbonitrile features a pyridine ring bearing both chlorine and nitrile substituents at the 4- and 2-positions, respectively. This configuration imparts strong electron-withdrawing character and enhances reactivity in nucleophilic substitution processes. The compound serves as a key building block in pharmaceutical synthesis and materials science due to its stability under standard conditions and compatibility with diverse reaction environments.

Synthesis

  • Route1
    • null|null
      1121-76-2
    • null|null
      7677-24-9
    • ~99%
    • In-stock
      4-Chloropyridine-2-carbonitrile|CS-W008318
      19235-89-3

    References

    • Takeda Chemical Industries, Ltd. Patent: EP1424336 A1, 2004 ; Location in patent: Page 219 ;
  • Route2

    References

    • Zhan, Wenhu; Li, Yanyang; Huang, Weiping; Zhao, Yanjin; Yao, Zhenglin; Yu, Shanyou; Yuan, Shoujun; Jiang, Falong; Yao, Shan; Li, Shuxin Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 14 p. 4323 - 4329
  • Route3
    • null|null
      1121-76-2
    • null|null
      79-44-7
    • ~99%
    • In-stock
      4-Chloropyridine-2-carbonitrile|CS-W008318
      19235-89-3

    References

    • PFIZER INC. Patent: EP1065206 A1, 2001 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   36.68
  • LogP   1.60668
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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