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Structure of 191595-63-8
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This trifluoromethyl-substituted nicotinic acid derivative features a strategically positioned hydroxyl group that enhances solubility and reactivity. The electron-withdrawing trifluoromethyl moiety modulates acidity and stability, enabling its use in synthetic routes to bioactive heterocycles and pharmaceutical intermediates under standard conditions.
2-Hydroxy-6-(trifluoromethyl)nicotinic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its trifluoromethyl group enhances metabolic stability and lipophilicity, while the ortho-hydroxyl and carboxylic acid functionalities provide sites for derivatization via esterification, amidation, or cyclization reactions. The compound exhibits good bench stability and facilitates efficient purification, making it well-suited for scalable synthesis workflows in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: