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(S)-1-Phenylpyrrolidin-3-amine dihydrochloride

  • CAS No. 1909294-50-3

  • Cat. No. CS-0200442
  • Molecule weight235.15
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(S)-1-Phenylpyrrolidin-3-amine dihydrochloride|CS-0200442

Structure of 1909294-50-3

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General Information

  • CAS No. 1909294-50-3
  • Cat. No. CS-0200442
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₆Cl₂N₂
  • Molecular Weight 235.15
  • Synonym(s) (3S)-1-Phenylpyrrolidin-3-amine dihydrochloride
  • SMILES N[C@@H]1CN(C2=CC=CC=C2)CC1.Cl.Cl

Description

(S)-1-Phenylpyrrolidin-3-amine dihydrochloride features a chiral pyrrolidine core bearing a phenyl group at the 1-position and a primary amine at the 3-position, delivering high enantioselectivity in asymmetric synthesis. The dihydrochloride salt enhances solubility and stability under standard bench conditions, enabling straightforward handling in medicinal chemistry workflows.

Application

(S)-1-Phenylpyrrolidin-3-amine dihydrochloride serves as a chiral building block for the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its well-defined stereochemistry and stable dihydrochloride salt form enable straightforward handling, purification, and incorporation into diverse coupling reactions. The molecule functions as a key scaffold in medicinal chemistry campaigns targeting CNS-directed therapeutics, offering high functional group tolerance and compatibility with standard synthetic protocols.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   29.26
  • LogP   2.0676
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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