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3-Aminopyrrolidin-2-one hydrochloride

  • CAS No. 117879-49-9

  • Cat. No. CS-0113495
  • Purity≥97%
  • MDL No.MFCD11506408

*For research and further manufacturing use only, not for direct human use.

3-Aminopyrrolidin-2-one hydrochloride|CS-0113495

Structure of 117879-49-9

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General Information

  • CAS No. 117879-49-9
  • Cat. No. CS-0113495
  • Purity ≥97%
  • MDL No. MFCD11506408
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₉ClN₂O
  • Molecular Weight 136.58
  • Synonym(s) 3-Aminopyrrolidin-2-one HCL
  • SMILES O=C1NCCC1N.[H]Cl

Description

3-Aminopyrrolidin-2-one hydrochloride is a bench-stable, moisture-tolerant heterocyclic amine featuring a pyrrolidinone core with a primary amine at the 3-position. This scaffold integrates readily into peptide-like sequences and serves as a key building block in medicinal chemistry for targeted receptor engagement and macrocyclization strategies.

Application

3-Aminopyrrolidin-2-one hydrochloride serves as a versatile building block in medicinal chemistry, enabling efficient access to saturated heterocyclic scaffolds. Its amine functionality facilitates direct derivatization and salt formation, enhancing solubility and handling. The pyrrolidinone core exhibits robust bench stability and compatibility with standard coupling reactions, supporting rapid library synthesis and structure–activity optimization in target-directed discovery workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501

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Computational Chemistry Data

  • TPSA   55.12
  • LogP   -0.7446
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

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