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CS-W001157 4
Total: USD 88.00

tert-Butyl 2-methyl-4-oxopiperidine-1-carboxylate

  • CAS No. 190906-92-4

  • Cat. No. CS-W001489
  • Purity≥97%
  • MDL No.MFCD04035608

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 2-methyl-4-oxopiperidine-1-carboxylate|CS-W001489

Structure of 190906-92-4

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General Information

  • CAS No. 190906-92-4
  • Cat. No. CS-W001489
  • Purity ≥97%
  • MDL No. MFCD04035608
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₉NO₃
  • Molecular Weight 213.27
  • Synonym(s) 2-METHYL-4-OXOPIPERIDINE, N-BOC PROTECTED
  • SMILES O=C1CCN(C(C1)C)C(=O)OC(C)(C)C

Description

tert-Butyl 2-methyl-4-oxopiperidine-1-carboxylate features a sterically hindered piperidine core with a ketone at the C4 position, enabling selective functionalization. The tert-butyl ester group provides stability and convenient deprotection under mild acidic conditions, making this scaffold valuable for building complex nitrogen-containing architectures in medicinal chemistry and natural product synthesis.

Application

tert-Butyl 2-methyl-4-oxopiperidine-1-carboxylate serves as a versatile building block in synthetic organic chemistry, enabling efficient access to substituted piperidines via reductive amination or nucleophilic addition at the C4 carbonyl. The tert-butyl carbamate group provides excellent stability and convenient removal under mild acidic conditions. Its bench-stable nature, functional group tolerance, and compatibility with standard coupling and reduction protocols make it ideal for medicinal chemistry and process development workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   46.61
  • LogP   1.9749
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   0

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