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(R)-2-Methylpiperidin-4-one hydrochloride

  • CAS No. 1434126-97-2

  • Cat. No. CS-0053488
  • Molecule weight149.62
  • Purity≥95%
  • MDL No.MFCD22682261

*For research and further manufacturing use only, not for direct human use.

(R)-2-Methylpiperidin-4-one hydrochloride|CS-0053488

Structure of 1434126-97-2

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General Information

  • CAS No. 1434126-97-2
  • Cat. No. CS-0053488
  • Purity ≥95%
  • MDL No. MFCD22682261
  • Storage RT, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₂ClNO
  • Molecular Weight 149.62
  • Synonym(s) 2-(R)-Methyl-4-piperidinone hydrochloride
  • SMILES Cl.C[C@@H]1CC(=O)CCN1

Description

(R)-2-Methylpiperidin-4-one hydrochloride is a chiral building block featuring a stereochemically defined piperidinone core with enhanced solubility and stability in aqueous media. This bench-stable, moisture-tolerant intermediate integrates readily into medicinal chemistry campaigns targeting CNS-active compounds and peptide mimetics, where its constrained conformation supports high binding affinity and metabolic resilience.

Application

(R)-2-Methylpiperidin-4-one hydrochloride serves as a chiral building block for medicinal chemistry, enabling efficient access to bioactive heterocycles. Its stable crystalline form facilitates handling and purification, while the ketone functionality supports diverse transformations including reductive amination, nucleophilic addition, and amide coupling. The stereochemically defined scaffold is well-suited for constructing pharmacologically relevant piperidine derivatives in drug discovery workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   29.1
  • LogP   0.7492
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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