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CS-W001157 4
Total: USD 88.00

3,3,3-Trifluoro-2,2-dimethylpropan-1-ol

  • CAS No. 1895296-01-1

  • Cat. No. CS-0162682
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3,3,3-Trifluoro-2,2-dimethylpropan-1-ol|CS-0162682

Structure of 1895296-01-1

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General Information

  • CAS No. 1895296-01-1
  • Cat. No. CS-0162682
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₉F₃O
  • Molecular Weight 142.12
  • Synonym(s) 3,3,3-Trifluoro-2,2-dimethylpropanol
  • SMILES OCC(C)(C)C(F)(F)F

Description

3,3,3-Trifluoro-2,2-dimethylpropan-1-ol is a fluorinated alcohol featuring a sterically shielded primary hydroxyl group. The trifluoromethyl substituent imparts strong electron-withdrawing character and enhanced stability. This structure enables robust participation in nucleophilic transformations while maintaining moisture-tolerant handling under standard conditions.

Application

3,3,3-Trifluoro-2,2-dimethylpropan-1-ol serves as a stable, bench-ready building block for fluorinated aliphatic scaffolds. Its trifluoromethyl group imparts enhanced metabolic stability and lipophilicity, while the tertiary alcohol functionality enables straightforward derivatization via esterification or ether formation. The molecule exhibits excellent functional group tolerance and facilitates efficient incorporation into complex synthetic sequences, making it a valuable reagent in medicinal chemistry and agrochemical research.

Safety Information

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GHS Pictogram :
GHS No : GHS02,GHS07
Signal Word : Danger
UN#: 1325
Class : 4.1
Packing Group : Ⅲ
Hazard Statements : H228-H315-H319-H335
Precautionary Statements : P210-P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

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Computational Chemistry Data

  • TPSA   20.23
  • LogP   1.5672
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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