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Structure of 188665-74-9
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This boronate ester integrates a stable tetramethyl-dioxaborolane moiety with a benzamide scaffold, enabling efficient Suzuki-Miyaura coupling under standard conditions. The para-substituted arylboronate features enhanced hydrolytic stability and moisture tolerance, simplifying handling in synthetic workflows.
3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide serves as a versatile boronate building block in Suzuki-Miyaura cross-coupling reactions. Its stability under ambient conditions and tolerance to diverse functional groups enable reliable C–C bond formation with aryl halides and pseudohalides. The dioxaborolane moiety facilitates efficient coupling while the amide functionality provides orthogonal reactivity for downstream derivatization, making it a practical scaffold for medicinal chemistry and materials synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P264-P270-P330-P501
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Lot numbers can be found on the outside label of a product: