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CS-W001157 4
Total: USD 88.00

(3-Carbamoylphenyl)boronic acid

  • CAS No. 351422-73-6

  • Cat. No. CS-W017897
  • Purity≥95%
  • MDL No.MFCD03411948

*For research and further manufacturing use only, not for direct human use.

(3-Carbamoylphenyl)boronic acid|CS-W017897

Structure of 351422-73-6

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General Information

  • CAS No. 351422-73-6
  • Cat. No. CS-W017897
  • Purity ≥95%
  • MDL No. MFCD03411948
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₈BNO₃
  • Molecular Weight 164.95
  • Synonym(s) BENZAMIDE-3-BORONIC ACID
  • SMILES NC(C1=CC(B(O)O)=CC=C1)=O

Description

(3-Carbamoylphenyl)boronic acid features a boronic acid group attached to a phenyl ring bearing a carbamoyl substituent at the meta position. This combination enables direct incorporation into Suzuki-Miyaura coupling reactions, where the electron-deficient aryl moiety enhances reactivity. The functionalized scaffold supports efficient synthesis of bioactive aryl amides and pharmaceutical intermediates under mild conditions.

Application

(3-Carbamoylphenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient access to biaryl scaffolds with retained functional group compatibility. Its boronic acid moiety facilitates reliable coupling under mild conditions, while the ortho-carbamoyl group offers enhanced solubility and stability, simplifying purification and improving handling for medicinal chemistry and process development workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   83.55
  • LogP   -1.5347
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   2

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