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CS-W001157 4
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(4R,4'R,5S,5'S)-2,2'-(1-Phenylpropane-2,2-diyl)bis(4,5-diphenyl-4,5-dihydrooxazole)

  • CAS No. 1884128-70-4

  • Cat. No. CS-0145114
  • Purity≥95%
  • MDL No.MFCD33022371

*For research and further manufacturing use only, not for direct human use.

(4R,4'R,5S,5'S)-2,2'-(1-Phenylpropane-2,2-diyl)bis(4,5-diphenyl-4,5-dihydrooxazole)|CS-0145114

Structure of 1884128-70-4

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General Information

  • CAS No. 1884128-70-4
  • Cat. No. CS-0145114
  • Purity ≥95%
  • MDL No. MFCD33022371
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃₉H₃₄N₂O₂
  • Molecular Weight 562.70
  • Synonym(s) None
  • SMILES CC(C1=N[C@H](C2=CC=CC=C2)[C@H](C3=CC=CC=C3)O1)(C4=N[C@H](C5=CC=CC=C5)[C@H](C6=CC=CC=C6)O4)CC7=CC=CC=C7

Description

This chiral bisoxazole scaffold features a rigid, sterically defined backbone with multiple aromatic substituents, enabling precise spatial control in asymmetric synthesis. The phenylpropane linker and diphenyl-substituted oxazole rings contribute to enhanced stability and defined molecular topology. Designed for use in catalyst design and molecular recognition applications, this structure offers high configurational integrity under standard bench conditions.

Application

This chiral diheterocycle serves as a robust, bench-stable scaffold for asymmetric synthesis, enabling stereoselective transformations via its rigid, multifunctional oxazole framework. Its orthogonal functional group tolerance facilitates sequential coupling and protection strategies in complex molecule assembly. The diphenyl-substituted dihydrooxazole units enhance solubility and crystallinity, simplifying purification. Functions effectively in transition-metal-catalyzed cross-couplings and as a building block in the construction of bioactive heterocyclic systems.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   43.18
  • LogP   9.058
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   8

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