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CS-W001157 4
Total: USD 88.00

(S,R)-Bn-BisPh-Sabox

  • CAS No. 2361262-50-0

  • Cat. No. CS-0145075
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(S,R)-Bn-BisPh-Sabox|CS-0145075

Structure of 2361262-50-0

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General Information

  • CAS No. 2361262-50-0
  • Cat. No. CS-0145075
  • Purity ≥95%
  • MDL No. None
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄₅H₃₈N₂O₂
  • Molecular Weight 638.80
  • Synonym(s) None
  • SMILES C1(C(CC2=CC=CC=C2)(CC3=CC=CC=C3)C4=N[C@@H](C5=CC=CC=C5)[C@@H](C6=CC=CC=C6)O4)=N[C@@H](C7=CC=CC=C7)[C@@H](C8=CC=CC=C8)O1

Description

(S,R)-Bn-BisPh-Sabox features a chiral bisphenyl scaffold with benzyl-protected amine functionality, enabling selective coupling in asymmetric synthesis. This bench-stable, moisture-tolerant reagent integrates seamlessly into catalytic systems requiring precise stereocontrol.

Application

(S,R)-Bn-BisPh-Sabox serves as a robust chiral bisphosphine ligand in palladium-catalyzed cross-coupling reactions, enabling efficient C–C bond formation under mild conditions. Its benzyl-protected bisphosphine architecture ensures excellent bench stability and ease of handling, while maintaining high enantioselectivity in asymmetric transformations. The ligand demonstrates broad functional group tolerance and facilitates catalyst turnover in Suzuki-Miyaura and Negishi couplings, making it a practical choice for complex molecule synthesis and API intermediate construction.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

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Computational Chemistry Data

  • TPSA   43.18
  • LogP   10.2808
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   10

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