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CS-W001157 4
Total: USD 88.00

Boc-Gly-Gly-Phe-Gly-OH

  • CAS No. 187794-49-6

  • Cat. No. CS-0039416
  • Purity≥96%
  • MDL No.MFCD02259478

*For research and further manufacturing use only, not for direct human use.

Boc-Gly-Gly-Phe-Gly-OH|CS-0039416

Structure of 187794-49-6

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General Information

  • CAS No. 187794-49-6
  • Cat. No. CS-0039416
  • Purity ≥96%
  • MDL No. MFCD02259478
  • Storage polypeptide, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₀H₂₈N₄O₇
  • Molecular Weight 436.46
  • Synonym(s) None
  • SMILES CC(C)(C)OC(NCC(NCC(N[C@H](C(NCC(O)=O)=O)CC1=CC=CC=C1)=O)=O)=O

Description

Boc-Gly-Gly-Phe-Gly-OH is a protected tetrapeptide intermediate featuring a C-terminal glycine residue and a Boc group at the N-terminus. This sequence incorporates a phenylalanine side chain flanked by glycine residues, offering a stable, bench-ready scaffold for peptide synthesis. The Boc protection ensures compatibility with standard deprotection protocols in solid-phase and solution-phase workflows.

Application

Boc-Gly-Gly-Phe-Gly-OH serves as a well-defined tetrapeptide building block for the synthesis of bioactive peptide sequences. The Boc group provides stable N-terminal protection, while the glycine residues offer conformational flexibility and compatibility with standard coupling protocols. This intermediate enables efficient solid-phase and solution-phase peptide assembly, particularly in the construction of cyclic or linear scaffolds relevant to protease inhibitor development and peptide-based drug discovery.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   162.93
  • LogP   -0.4444
  • H_Acceptors   6
  • H_Donors   5
  • Rotatable_Bonds   10

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