Fomc-Gly-Gly-Phe-Gly-OH

Name: Fomc-Gly-Gly-Phe-Gly-OH
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CAS No. 1817857-75-2
Cat. No. CS-0646870
Purity≥98%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Structure of 1817857-75-2

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General Information

CAS No. 1817857-75-2
Cat. No. CS-0646870
Purity ≥98%
MDL No. None
Storage polypeptide, sealed storage, away from moisture
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₃₀H₃₀N₄O₇
Molecular Weight 558.58
Synonym(s) None
SMILES OC(CNC([C@H](CC1=CC=CC=C1)NC(CNC(CNC(OCC2C3=CC=CC=C3C4=CC=CC=C42)=O)=O)=O)=O)=O

Description

Fomc-Gly-Gly-Phe-Gly-OH features a formylated N-terminus paired with a tetrapeptide sequence optimized for stability and solubility. This peptide moiety integrates a hydrophobic phenylalanine residue flanked by glycines, enabling efficient conjugation workflows while maintaining robustness under standard bench conditions.

Application

Fomc-Gly-Gly-Phe-Gly-OH serves as a protected tetrapeptide building block for solid-phase peptide synthesis, featuring a formylmethyl (Fomc) group at the N-terminus and C-terminal carboxamide functionality. Its sequence enables efficient incorporation into bioactive peptide scaffolds, with demonstrated stability during coupling steps and compatibility with standard deprotection protocols. The glycine-rich motif offers conformational flexibility, while phenylalanine provides aromatic handle for structural probing or conjugation.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Computational Chemistry Data

TPSA 162.93
LogP 1.5696
H_Acceptors 6
H_Donors 5
Rotatable_Bonds 12

Other Classifications

Bioactive Molecules Peptides

Life Science Amino Acids and their Derivatives Phenylalanine and derivatives

Life Science ADC Related Compound ADC Linker

Building Blocks Functional Group Fmoc

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Antibody-Drug Conjugates (ADC) Preparation Research Reagents Cross-Linkers

Biochemistry Pharmaceutical Development and Drug Discovery Research Antibody-Drug Conjugates (ADC) Preparation Research Reagents Cross-Linkers

Biochemistry Biochemicals and Reagents Antibody-Drug Conjugates (ADC) Preparation Research Reagents Cross-Linkers

Key Words

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Fomc-Gly-Gly-Phe-Gly-OH

CAS No. 1817857-75-2

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