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CS-W001157 4
Total: USD 88.00

(3-Chloronaphthalen-2-yl)boronic acid

  • CAS No. 1873273-39-2

  • Cat. No. CS-0108651
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(3-Chloronaphthalen-2-yl)boronic acid|CS-0108651

Structure of 1873273-39-2

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General Information

  • CAS No. 1873273-39-2
  • Cat. No. CS-0108651
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₈BClO₂
  • Molecular Weight 206.43
  • Synonym(s) None
  • SMILES OB(C1=C(Cl)C=C2C=CC=CC2=C1)O

Description

This boronate moiety integrates seamlessly into Suzuki-Miyaura cross-coupling reactions, delivering naphthalene-based architectures with high efficiency. The chlorine substituent enables orthogonal functionalization, while the bench-stable nature simplifies handling and storage under standard conditions.

Application

(3-Chloronaphthalen-2-yl)boronic acid serves as a versatile building block in palladium-catalyzed cross-coupling reactions, enabling efficient C–C bond formation under standard Suzuki-Miyaura conditions. The naphthalene scaffold provides structural rigidity and π-conjugation, while the boronic acid functionality offers excellent bench stability, compatibility with diverse functional groups, and straightforward purification via crystallization or chromatography. Its utility spans synthetic organic chemistry, materials science, and pharmaceutical development, particularly in constructing biaryl architectures common in advanced intermediates and active pharmaceutical ingredients.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   1.173
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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