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CS-W001157 4
Total: USD 88.00

(8-Chloronaphthalen-1-yl)boronic acid

  • CAS No. 2305022-53-9

  • Cat. No. CS-0113568
  • Purity≥97%
  • MDL No.MFCD18411302

*For research and further manufacturing use only, not for direct human use.

(8-Chloronaphthalen-1-yl)boronic acid|CS-0113568

Structure of 2305022-53-9

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General Information

  • CAS No. 2305022-53-9
  • Cat. No. CS-0113568
  • Purity ≥97%
  • MDL No. MFCD18411302
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₈BClO₂
  • Molecular Weight 206.43
  • Synonym(s) None
  • SMILES ClC1=CC=CC2=C1C(B(O)O)=CC=C2

Description

This boronate moiety integrates readily into Suzuki-Miyaura cross-coupling reactions, delivering functionalized naphthalene derivatives with high efficiency. The chlorine substituent enhances reactivity and enables sequential transformations, while the bench-stable nature simplifies handling in synthetic workflows.

Application

(8-Chloronaphthalen-1-yl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient C–C bond formation with aryl and vinyl halides. Its boronic acid functionality exhibits good bench stability and compatibility with diverse functional groups, facilitating the synthesis of complex biaryl systems relevant to pharmaceutical and materials chemistry. The chlorine substituent provides orthogonal reactivity for further functionalization.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   1.173
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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