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CS-W001157 4
Total: USD 88.00

1,1'-Oxalyldiimidazole

  • CAS No. 18637-83-7

  • Cat. No. CS-0204873
  • Purity≥98%
  • MDL No.MFCD00043067

*For research and further manufacturing use only, not for direct human use.

1,1'-Oxalyldiimidazole|CS-0204873

Structure of 18637-83-7

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General Information

  • CAS No. 18637-83-7
  • Cat. No. CS-0204873
  • Purity ≥98%
  • MDL No. MFCD00043067
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₆N₄O₂
  • Molecular Weight 190.16
  • Synonym(s) 1,1-Oxalyldiimidazole
  • SMILES O=C(C(=O)N1C=NC=C1)N2C=NC=C2

Description

1,1'-Oxalyldiimidazole serves as a robust coupling agent for amine functionalization, featuring a rigid oxalyl bridge that enhances reactivity and stability. This bifunctional imidazole derivative enables efficient amidation under mild conditions, offering high yield and minimal side reactions in synthetic workflows.

Synthesis

  • Route1
    • Imidazole Ondansetron Impurity|CS-0229601
      288-32-4
    • null|null
      79-37-8
    • ~%
    • In-stock
      1,1'-Oxalyldiimidazole|CS-0204873
      18637-83-7

    References

    • Chemistry Letters, , p. 1819 - 1820
  • Route2
    • null|null
      79-37-8
    • null|null
      18156-74-6
    • ~94%
    • In-stock
      1,1'-Oxalyldiimidazole|CS-0204873
      18637-83-7

    References

    • Murata, Shizuaki Chemistry Letters, 1983 , p. 1819 - 1820
  • Route3
    • null|null
      71638-08-9
    • ~0%
    • null|null
      1135-98-4
    • In-stock
      1,1'-Oxalyldiimidazole|CS-0204873
      18637-83-7

    References

    • Dabkowski, Wojciech; Michalski, Jan; Wasiak, Jacek; Cramer, Friedrich Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1994 , # 7 p. 817 - 820

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3259
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302-H312-H314
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   69.78
  • LogP   0.0602
  • H_Acceptors   6
  • H_Donors   0
  • Rotatable_Bonds   0

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