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CS-W001157 4
Total: USD 88.00

8-(2-Hydroxybenzamido)octanoic acid

  • CAS No. 183990-46-7

  • Cat. No. CS-0720595
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

8-(2-Hydroxybenzamido)octanoic acid|CS-0720595

Structure of 183990-46-7

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General Information

  • CAS No. 183990-46-7
  • Cat. No. CS-0720595
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₂₁NO₄
  • Molecular Weight 279.33
  • Synonym(s) None
  • SMILES OC(=O)CCCCCCCNC(=O)C1=CC=CC=C1O

Description

8-(2-Hydroxybenzamido)octanoic acid features a carboxylic acid terminus paired with a salicylamide moiety, enabling dual functionality in conjugation workflows. The ortho-hydroxy group facilitates intramolecular hydrogen bonding, enhancing structural rigidity and solubility under standard conditions. This derivative serves as a modular linker for peptide synthesis and bioconjugation, offering improved stability and predictable reactivity in aqueous environments.

Application

8-(2-Hydroxybenzamido)octanoic acid serves as a versatile bifunctional building block for peptide and macrocyclic scaffold synthesis, combining a carboxylic acid for coupling reactions with an ortho-hydroxybenzamide group enabling hydrogen bonding and metal coordination. Its stability under standard conditions facilitates purification and integration into complex molecular architectures.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319
Precautionary Statements : P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501

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Computational Chemistry Data

  • TPSA   86.63
  • LogP   2.5472
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   9

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