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CS-W001157 4
Total: USD 88.00

2-Methylbut-3-enoic acid,98% stabilized with MEHQ

  • CAS No. 53774-20-2

  • Cat. No. CS-0006592
  • Purity97% (stabilized with MEHQ)
  • MDL No.MFCD00042650

*For research and further manufacturing use only, not for direct human use.

2-Methylbut-3-enoic acid,98% stabilized with MEHQ|CS-0006592

Structure of 53774-20-2

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General Information

  • CAS No. 53774-20-2
  • Cat. No. CS-0006592
  • Purity 97% (stabilized with MEHQ)
  • MDL No. MFCD00042650
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₈O₂
  • Molecular Weight 100.12
  • Synonym(s) CH2=CHCH(CH3)COOH
  • SMILES C=CC(C)C(O)=O

Description

2-Methylbut-3-enoic acid (98%, stabilized with MEHQ) features a conjugated enoic system with a methyl-substituted alkene, offering enhanced reactivity in Diels-Alder and Michael addition reactions. The MEHQ stabilization prevents polymerization during storage and handling, ensuring reliable performance under standard bench conditions.

Application

2-Methylbut-3-enoic acid (stabilized with MEHQ) serves as a versatile building block for conjugated unsaturated systems, enabling efficient Michael additions and Diels-Alder reactions. Its stabilized enoic acid structure exhibits enhanced bench stability and compatibility with common functional groups, facilitating straightforward purification and integration into synthetic sequences targeting heterocyclic scaffolds and bioactive molecules.

Synthesis

  • Route1
    • null|null
      563-52-0
    • null|null
      124-38-9
    • ~67%
    • In-stock
      2-Methylbut-3-enoic acid,98% stabilized with MEHQ|CS-0006592
      53774-20-2

    References

    • European Journal of Organic Chemistry, , # 26 p. 4405 - 4411
  • Route2
    • null|null
      124-38-9
    • In-stock
      (E)-2-(But-2-en-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane|CS-0129386
      69611-02-5
    • ~80%
    • In-stock
      2-Methylbut-3-enoic acid,98% stabilized with MEHQ|CS-0006592
      53774-20-2

    References

    • Organic Letters, , vol. 15, # 15 p. 4034 - 4037
  • Route3
    • null|null
      69079-28-3
    • ~92%
    • In-stock
      2-Methylbut-3-enoic acid,98% stabilized with MEHQ|CS-0006592
      53774-20-2

    References

    • Synthesis, , # 21 art. no. T09008SS, p. 3443 - 3446

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3265
Class : 8
Packing Group : Ⅱ
Hazard Statements : H227-H290-H314
Precautionary Statements : P210-P234-P260-P264-P280-P301+P330+P331-P304+P340-P363-P370+P378-P390-P405-P406-P501

Quality Control

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   0.8931
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   2

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