Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

4-Fluoro-3-hydroxybenzonitrile

  • CAS No. 186590-04-5

  • Cat. No. CS-W005781
  • Purity≥97%
  • MDL No.MFCD08689519

*For research and further manufacturing use only, not for direct human use.

4-Fluoro-3-hydroxybenzonitrile|CS-W005781

Structure of 186590-04-5

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 186590-04-5
  • Cat. No. CS-W005781
  • Purity ≥97%
  • MDL No. MFCD08689519
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₄FNO
  • Molecular Weight 137.11
  • Synonym(s) 4-FLUORO-3-HYDROXYBENZONITRILE 98
  • SMILES N#CC1=CC=C(F)C(O)=C1

Description

4-Fluoro-3-hydroxybenzonitrile features a strategically positioned hydroxyl group flanked by fluorine and nitrile functionalities, enabling direct incorporation into bioactive scaffolds. The electron-withdrawing nitrile and fluorine atoms enhance metabolic stability while maintaining solubility under standard conditions. This ortho-substituted aryl system serves as a key building block for pharmaceutical intermediates and functionalized heterocycles.

Application

4-Fluoro-3-hydroxybenzonitrile serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the phenolic hydroxyl group and facilitating downstream coupling reactions. Its ortho-fluorine and nitrile groups provide orthogonal reactivity for palladium-catalyzed cross-couplings and nucleophilic substitutions. Bench-stable and amenable to purification via recrystallization, it functions reliably in the synthesis of heterocyclic scaffolds and bioactive intermediates.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   44.02
  • LogP   1.40298
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 4-Fluoro-3-hydroxybenzonitrile sigma4-Fluoro-3-hydroxybenzonitrile manufacturer4-Fluoro-3-hydroxybenzonitrile price4-Fluoro-3-hydroxybenzonitrile structure4-Fluoro-3-hydroxybenzonitrile SDSbuy 4-Fluoro-3-hydroxybenzonitrile4-Fluoro-3-hydroxybenzonitrile supplier4-Fluoro-3-hydroxybenzonitrile uses4-Fluoro-3-hydroxybenzonitrile molecular weightprice of 4-Fluoro-3-hydroxybenzonitrile4-Fluoro-3-hydroxybenzonitrile chemical name formula of 4-Fluoro-3-hydroxybenzonitrile
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label