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Structure of 51446-31-2
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4-Fluoro-3-hydroxybenzoic acid features a strategically positioned fluorine atom and hydroxyl group on the aromatic ring, enabling enhanced electronic modulation and hydrogen bonding capacity. This combination supports efficient incorporation into bioactive scaffolds and facilitates downstream functionalization in medicinal chemistry campaigns under standard conditions.
4-Fluoro-3-hydroxybenzoic acid serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles and pharmaceutical scaffolds. Its ortho-hydroxyl and para-fluoro substituents provide complementary reactivity for palladium-catalyzed coupling, electrophilic substitution, and directed metalation. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis workflows in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501
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Lot numbers can be found on the outside label of a product: