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Structure of 1858215-94-7
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This boronate moiety integrates a 5-fluoro-6-methyl-3-pyridyl scaffold, delivering enhanced stability and solubility in polar solvents. The electron-deficient pyridine ring enables efficient coupling in Suzuki-Miyaura reactions, while the methyl and fluorine substituents modulate reactivity and metabolic resistance.
(5-Fluoro-6-methyl-3-pyridyl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl and heteroaryl scaffolds. The fluorine and methyl substituents provide orthogonal electronic tuning and enhanced metabolic stability in medicinal chemistry applications. Bench-stable and readily purified by recrystallization, it exhibits broad functional group tolerance and reliable coupling efficiency under standard reaction conditions.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362
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Lot numbers can be found on the outside label of a product: