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ethyl 4-(ethylamino)-2-(methylthio)pyrimidine-5-carboxylate

  • CAS No. 185040-33-9

  • Cat. No. CS-0448947
  • Molecule weight241.31
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

ethyl 4-(ethylamino)-2-(methylthio)pyrimidine-5-carboxylate|CS-0448947

Structure of 185040-33-9

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General Information

  • CAS No. 185040-33-9
  • Cat. No. CS-0448947
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₅N₃O₂S
  • Molecular Weight 241.31
  • Synonym(s) ethyl 4-(ethylamino)-2-methylsulfanylpyrimidine-5-carboxylate
  • SMILES O=C(OCC)C1=CN=C(N=C1NCC)SC

Synthesis

  • Route1
    • Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate Avanafil  Impurity|CS-0228709
      5909-24-0
    • null|null
      75-04-7
    • ~98%
    • ethyl 4-(ethylamino)-2-(methylthio)pyrimidine-5-carboxylate|CS-0448947
      185040-33-9

    References

    • DECIPHERA PHARMACEUTICALS, LLC Patent: WO2008/33999 A2, 2008 ; Location in patent: Page/Page column 89 ;

Safety Information

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Hazard Statements : N/A
Precautionary Statements : N/A

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Computational Chemistry Data

  • TPSA   64.11
  • LogP   1.807
  • H_Acceptors   6
  • H_Donors   1
  • Rotatable_Bonds   5

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