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CS-W001157 4
Total: USD 88.00

ethyl 4-methylamino-2-methyl-thiopyrimidine-5-carboxylate

  • CAS No. 76360-82-2

  • Cat. No. CS-W000293
  • Purity≥97%
  • MDL No.MFCD00476788

*For research and further manufacturing use only, not for direct human use.

ethyl 4-methylamino-2-methyl-thiopyrimidine-5-carboxylate|CS-W000293

Structure of 76360-82-2

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General Information

  • CAS No. 76360-82-2
  • Cat. No. CS-W000293
  • Purity ≥97%
  • MDL No. MFCD00476788
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₃N₃O₂S
  • Molecular Weight 227.28
  • Synonym(s) Ethyl 4-(methylamino)-2-(methylthio)pyrimidine-5-carboxylate
  • SMILES CCOC(=O)c1cnc(SC)nc1NC

Synthesis

  • Route1
    • Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate Avanafil  Impurity|CS-0228709
      5909-24-0
    • null|null
      74-89-5
    • ~94%
    • In-stock
      ethyl 4-methylamino-2-methyl-thiopyrimidine-5-carboxylate|CS-W000293
      76360-82-2

    References

    • Goldstein, David M.; Soth, Michael; Gabriel, Tobias; Dewdney, Nolan; Kuglstatter, Andreas; Arzeno, Humberto; Chen, Jeffrey; Bingenheimer, William; Dalrymple, Stacie A.; Dunn, James; Farrell, Robert; Frauchiger, Sandra; La Fargue, Joann; Ghate, Manjiri; Graves, Bradford; Hill, Ronald J.; Li, Fujun; Litman, Renee; Loe, Brad; McIntosh, Joel; McWeeney, Daniel; Papp, Eva; Park, Jaehyeon; Reese, Harlan F.; Roberts, Richard T.; Rotstein, David; San Pablo, Bong; Sarma, Keshab; Stahl, Martin; Sung, Man-Ling; Suttman, Rebecca T.; Sjogren, Eric B.; Tan, Yunchou; Trejo, Alejandra; Welch, Mary; Weller, Paul; Wong, Brian R.; Zecic, Hasim Journal of Medicinal Chemistry, 2011 , vol. 54, # 7 p. 2255 - 2265
  • Route2
    • Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate Avanafil  Impurity|CS-0228709
      5909-24-0
    • ~%
    • In-stock
      ethyl 4-methylamino-2-methyl-thiopyrimidine-5-carboxylate|CS-W000293
      76360-82-2

    References

    • US2003/171584 A1, ;
  • Route3
    • Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate Avanafil  Impurity|CS-0228709
      5909-24-0
    • null|null
      593-51-1
    • ~%
    • In-stock
      ethyl 4-methylamino-2-methyl-thiopyrimidine-5-carboxylate|CS-W000293
      76360-82-2

    References

    • WO2011/75616 A1, ; Page/Page column 62 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H319
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   64.11
  • LogP   1.4169
  • H_Acceptors   6
  • H_Donors   1
  • Rotatable_Bonds   4

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