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Structure of 182692-69-9
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5-Bromo-2-nitrothiazole features a bromine substituent at the 5-position and a nitro group at the 2-position on the thiazole ring, creating a highly electron-deficient heterocycle. This combination enables direct functionalization in cross-coupling reactions and facilitates incorporation into bioactive scaffolds. The molecule exhibits excellent stability under standard bench conditions, making it a reliable building block for medicinal chemistry and materials science applications.
5-Bromo-2-nitrothiazole serves as a versatile building block in medicinal chemistry and heterocyclic synthesis, enabling efficient diversification via palladium-catalyzed cross-coupling reactions. The bromine and nitro groups provide orthogonal reactivity for sequential functionalization, while the thiazole core offers metabolic stability and favorable pharmacophoric properties. Bench-stable and amenable to standard purification methods, it functions reliably in multi-step syntheses targeting bioactive scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: