5-Chloro-7-methoxypyrazolo[1,5-a]pyrimidine

Name: 5-Chloro-7-methoxypyrazolo[1,5-a]pyrimidine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1824286-23-8
Cat. No. CS-0097475
Purity≥96%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

5-Chloro-7-methoxypyrazolo[1,5-a]pyrimidine|CS-0097475

Structure of 1824286-23-8

Size

Price

Quantity

* Please select Quantity before adding items.

Description

5-Chloro-7-methoxypyrazolo[1,5-a]pyrimidine features a fused heterocyclic core with complementary electron-withdrawing and donor substituents, enabling selective coupling in late-stage functionalization. The chloro group at C5 facilitates palladium-catalyzed cross-coupling, while the methoxy moiety enhances solubility and modulates electronic properties. This scaffold serves as a key building block for kinase inhibitors and bioactive small molecules.

Application

5-Chloro-7-methoxypyrazolo[1,5-a]pyrimidine serves as a versatile building block in medicinal chemistry, enabling efficient construction of heterocyclic scaffolds via palladium-catalyzed cross-coupling reactions. Its chloro group facilitates nucleophilic substitution under mild conditions, while the methoxy functionality enhances solubility and modulates electronic properties. The scaffold exhibits excellent bench stability and compatibility with diverse functional groups, making it ideal for iterative synthesis campaigns targeting kinase inhibitors and other bioactive molecules.

General Information

CAS No. 1824286-23-8
Cat. No. CS-0097475
Purity ≥96%
MDL No. None
Storage 4°C, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₆ClN₃O
Molecular Weight 183.60
Synonym(s) None
SMILES COC1=CC(Cl)=NC2=CC=NN12

Computational Chemistry Data

TPSA 39.42
LogP 1.3913
H_Acceptors 4
H_Donors 0
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyrazole compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyrimidine compounds

Key Words

1824286-23-8 sigma1824286-23-8 manufacturer1824286-23-8 price1824286-23-8 structure1824286-23-8 SDSbuy 1824286-23-81824286-23-8 supplier1824286-23-8 uses1824286-23-8 molecular weightprice of 1824286-23-81824286-23-8 chemical name formula of 1824286-23-8

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

5-Chloro-7-methoxypyrazolo[1,5-a]pyrimidine

CAS No. 1824286-23-8

Recommended Products