Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

4-Bromomethylbenzaldehyde

  • CAS No. 51359-78-5

  • Cat. No. CS-0038637
  • Purity≥97%
  • MDL No.MFCD08271963

*For research and further manufacturing use only, not for direct human use.

4-Bromomethylbenzaldehyde|CS-0038637

Structure of 51359-78-5

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 51359-78-5
  • Cat. No. CS-0038637
  • Purity ≥97%
  • MDL No. MFCD08271963
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₇BrO
  • Molecular Weight 199.05
  • Synonym(s) 4-(Bromomethyl)benzaldehyde
  • SMILES C1=C(C=CC(=C1)C=O)CBr

Description

4-Bromomethylbenzaldehyde features a bromomethyl group flanked by an aldehyde functionality, enabling direct functionalization at the benzylic position. This dual-reactive architecture supports efficient coupling in cross-coupling reactions and facilitates synthesis of advanced intermediates for pharmaceuticals and functional materials under standard conditions.

Application

4-Bromomethylbenzaldehyde serves as a versatile building block in synthetic organic chemistry, enabling efficient construction of biaryl and heterocyclic scaffolds. The bromomethyl group facilitates Suzuki-Miyaura and Stille couplings, while the aldehyde functionality supports reductive amination, oxime formation, and Mannich reactions. Its bench-stable nature and compatibility with diverse functional groups make it ideal for iterative synthesis in medicinal chemistry and materials science workflows.

Synthesis

  • Route1

    References

    • Wang, Xiang-Zhu; Burke Jr., Terrence R. Synlett, 2004 , # 3 p. 469 - 472
  • Route2

    References

    • LIGHTSHIP MEDICAL LIMITED; JAMES, Tony; BARWELL, Nicholas, Paul Patent: WO2012/95628 A1, 2012 ; Location in patent: Page/Page column 16 ;
  • Route3

    References

    • VERTEX PHARMACEUTICALS INCORPORATED; CHARRIER, Jean-Damien; BINCH, Haley, Marie; HURLEY, Dennis, James; CLEVELAND, Thomas; JOSHI, Pramod; FANNING, Lev Tyler, Dewey; PINDER, Joanne; O'DONNELL, Michael; VIRANI, Anisa, Nizarali; KNEGTEL, Ronald, Marcellus Alphonsus; DURRANT, Steven, John; YOUNG, Stephen, Clinton; PIERRE-HENRI; KAY, David; REAPER, Philip, Michael Patent: WO2011/143426 A1, 2011 ; Location in patent: Page/Page column 76-77 ; WO 2011/143426 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302-H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   17.07
  • LogP   2.394
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 4-Bromomethylbenzaldehyde sigma4-Bromomethylbenzaldehyde manufacturer4-Bromomethylbenzaldehyde price4-Bromomethylbenzaldehyde structure4-Bromomethylbenzaldehyde SDSbuy 4-Bromomethylbenzaldehyde4-Bromomethylbenzaldehyde supplier4-Bromomethylbenzaldehyde uses4-Bromomethylbenzaldehyde molecular weightprice of 4-Bromomethylbenzaldehyde4-Bromomethylbenzaldehyde chemical name formula of 4-Bromomethylbenzaldehyde
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label