Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

4-Fluoro-3-(trifluoromethyl)phenylboronic acid

  • CAS No. 182344-23-6

  • Cat. No. CS-W015250
  • Purity≥98%
  • MDL No.MFCD07363787

*For research and further manufacturing use only, not for direct human use.

4-Fluoro-3-(trifluoromethyl)phenylboronic acid|CS-W015250

Structure of 182344-23-6

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 182344-23-6
  • Cat. No. CS-W015250
  • Purity ≥98%
  • MDL No. MFCD07363787
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅BF₄O₂
  • Molecular Weight 207.92
  • Synonym(s) 4-Fluoro-3-(trifluoromethyl)benzeneboronic Acid (contains varying amounts of Anhydride)
  • SMILES C1=C(C=CC(=C1C(F)(F)F)F)B(O)O

Description

4-Fluoro-3-(trifluoromethyl)phenylboronic acid features a fluorinated aryl core with a trifluoromethyl group at the meta position and a boronic acid handle at the para site. This electron-deficient scaffold integrates readily into Suzuki-Miyaura couplings, offering enhanced reactivity and stability under standard conditions. The molecule exhibits improved solubility in polar solvents and maintains bench-stability during handling.

Application

4-Fluoro-3-(trifluoromethyl)phenylboronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl scaffolds. Its trifluoromethyl group enhances metabolic stability and lipophilicity, while the fluorine substituent offers favorable electronic effects and ortho-directing capability. The boronic acid functionality provides excellent bench stability, mild reaction conditions, and compatibility with diverse functional groups, facilitating streamlined synthesis of complex aromatic systems relevant to pharmaceutical and agrochemical development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   40.46
  • LogP   0.5243
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 182344-23-6 sigma182344-23-6 manufacturer182344-23-6 price182344-23-6 structure182344-23-6 SDSbuy 182344-23-6182344-23-6 supplier182344-23-6 uses182344-23-6 molecular weightprice of 182344-23-6182344-23-6 chemical name formula of 182344-23-6
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label