(2R,4R)-2-methyltetrahydro-2H-pyran-4-ol

Name: (2R,4R)-2-methyltetrahydro-2H-pyran-4-ol
Brand: ChemScene
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CAS No. 1821720-33-5
Cat. No. CS-0472514
Molecule weight116.16
Purity≥98%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
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(2R,4R)-2-methyltetrahydro-2H-pyran-4-ol|CS-0472514

Structure of 1821720-33-5

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General Information

CAS No. 1821720-33-5
Cat. No. CS-0472514
Purity ≥98%
MDL No. None
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₁₂O₂
Molecular Weight 116.16
Synonym(s) None
SMILES C[C@@H]1C[C@H](O)CCO1

Description

This chiral tetrahydropyran alcohol features a rigid, oxygen-containing ring with defined stereochemistry at the 2- and 4-positions. The methyl group at C2 imparts steric bias, while the hydroxyl at C4 enables selective derivatization. Bench-stable and moisture-tolerant, this scaffold integrates readily into complex molecular architectures for natural product synthesis and medicinal chemistry applications.

Application

(2R,4R)-2-methyltetrahydro-2H-pyran-4-ol serves as a chiral building block for the synthesis of bioactive molecules, offering predictable stereocontrol in glycosylation and cyclization reactions. Its bench-stable, crystalline nature facilitates handling and purification, while the hydroxyl and methyl groups enable selective functionalization. Functions as a key intermediate in carbohydrate mimetics and natural product derivatives.

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

TPSA 29.46
LogP 0.5462
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 0

Other Classifications

Building Blocks Skeleton Aliphatic heterocycle compounds Tetrahydropyran compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(2R,4R)-2-methyltetrahydro-2H-pyran-4-ol

CAS No. 1821720-33-5

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