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CS-W001157 4
Total: USD 88.00

Quinolin-2-ol

  • CAS No. 70254-42-1

  • Cat. No. CS-0513751
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Quinolin-2-ol|CS-0513751

Structure of 70254-42-1

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General Information

  • CAS No. 70254-42-1
  • Cat. No. CS-0513751
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₇NO
  • Molecular Weight 145.16
  • Synonym(s) 2-QUINOLINOL
  • SMILES OC1=NC2=CC=CC=C2C=C1

Description

Quinolin-2-ol serves as a key heterocyclic scaffold in medicinal chemistry, featuring a hydroxyl group at the 2-position that enables facile derivatization. This arrangement imparts enhanced solubility and facilitates hydrogen bonding in target engagement. The molecule exhibits bench-stable behavior under standard conditions and integrates readily into synthetic routes for bioactive compounds.

Application

Quinolin-2-ol serves as a versatile building block in heterocyclic synthesis, enabling efficient access to quinoline-based scaffolds through established transformations. Its phenolic functionality facilitates direct functionalization, while the nitrogen atom supports regioselective electrophilic substitution and coordination in catalytic systems. The compound exhibits sufficient bench stability for routine handling and is compatible with common purification methods, making it a practical choice for medicinal chemistry and process development workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   33.12
  • LogP   1.9404
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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