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Structure of 181955-79-3
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This piperazine derivative features two tert-butoxycarbonyl-protected amine groups flanking a carboxylic acid at the 2-position, enabling selective deprotection and conjugation. The bulky tert-butyl ester moieties enhance solubility and stability during synthetic manipulations. Ideal for modular peptide coupling and macrocyclic scaffold construction under standard conditions.
1,4-Bis(tert-butoxycarbonyl)piperazine-2-carboxylic acid serves as a versatile dipeptide-like building block for the synthesis of complex heterocyclic scaffolds and peptidomimetics. Its two orthogonal tert-butyl carbamate groups enable sequential deprotection and functionalization, while the carboxylic acid facilitates amide coupling. The molecule exhibits excellent bench stability and simplifies purification in multi-step syntheses, making it ideal for medicinal chemistry campaigns requiring precise control over substitution patterns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H317-H319
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Precautionary Statements : P261-P264-P272-P280-P302+P352-P363-P501
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Lot numbers can be found on the outside label of a product: