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CS-W001157 4
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1,1-Dimethylethyl N-(cis-4-formylcyclohexyl)carbamate

  • CAS No. 181308-56-5

  • Cat. No. CS-0255527
  • Purity≥97%
  • MDL No.MFCD03844599

*For research and further manufacturing use only, not for direct human use.

1,1-Dimethylethyl N-(cis-4-formylcyclohexyl)carbamate|CS-0255527

Structure of 181308-56-5

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General Information

  • CAS No. 181308-56-5
  • Cat. No. CS-0255527
  • Purity ≥97%
  • MDL No. MFCD03844599
  • Storage -20°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₂₁NO₃
  • Molecular Weight 227.30
  • Synonym(s) Cis-tert-butyl N-(4-formylcyclohexyl)carbamate
  • SMILES O=C(OC(C)(C)C)N[C@H]1CC[C@@H](C=O)CC1

Description

N-(Azido-PEG3)-N-Boc-PEG3-NHS ester is a branched PEGylation linker. The azide group allows for Click Chemistry reactions to take place. The Boc-protected amine can be deprotected under acidic conditions. The NHS ester can react with primary amines.

Synthesis

  • Route1

    References

    • Witherington, Jason; Bordas, Vincent; Cooper, Dave G.; Forbes, Ian T.; Gribble, Andrew D.; Ife, Robert J.; Berkhout, Theo; Gohil, Jayneeta; Groot, Pieter H.E. Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 16 p. 2177 - 2180
  • Route2

    References

    • Witherington, Jason; Bordas, Vincent; Cooper, Dave G.; Forbes, Ian T.; Gribble, Andrew D.; Ife, Robert J.; Berkhout, Theo; Gohil, Jayneeta; Groot, Pieter H.E. Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 16 p. 2177 - 2180
  • Route3

    References

    • Witherington, Jason; Bordas, Vincent; Cooper, Dave G.; Forbes, Ian T.; Gribble, Andrew D.; Ife, Robert J.; Berkhout, Theo; Gohil, Jayneeta; Groot, Pieter H.E. Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 16 p. 2177 - 2180

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

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Computational Chemistry Data

  • TPSA   55.4
  • LogP   2.2688
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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