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CS-W001157 4
Total: USD 88.00

4-((tert-Butoxycarbonyl)amino)cyclohexanecarboxylic acid

  • CAS No. 130309-46-5

  • Cat. No. CS-W021980
  • Molecule weight243.30
  • Purity≥98%
  • MDL No.MFCD03453262

*For research and further manufacturing use only, not for direct human use.

4-((tert-Butoxycarbonyl)amino)cyclohexanecarboxylic acid|CS-W021980

Structure of 130309-46-5

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General Information

  • CAS No. 130309-46-5
  • Cat. No. CS-W021980
  • Purity ≥98%
  • MDL No. MFCD03453262
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₂₁NO₄
  • Molecular Weight 243.30
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)NC1CCC(C(=O)O)CC1

Description

This cyclohexanecarboxylic acid derivative features a tert-butoxycarbonyl-protected amine group, offering enhanced stability and ease of handling in synthetic workflows. The bulky Boc moiety enables selective deprotection under mild acidic conditions, facilitating downstream functionalization. Ideal for peptide coupling and medicinal chemistry applications requiring controlled nitrogen protection.

Application

4-((tert-Butoxycarbonyl)amino)cyclohexanecarboxylic acid serves as a versatile building block for the synthesis of bioactive cyclohexane-containing scaffolds. The tert-butoxycarbonyl (Boc) group provides excellent stability and orthogonal deprotection under mild acidic conditions, enabling efficient incorporation into peptide-like sequences and heterocyclic frameworks. Its carboxylic acid functionality facilitates direct coupling reactions, while the cyclohexane ring offers conformational rigidity useful in medicinal chemistry optimization. This compound enables robust, high-yielding transformations in standard synthetic workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   75.63
  • LogP   2.1545
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

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