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CS-W001157 4
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2,4-Dichloroimidazo[2,1-f][1,2,4]triazine

  • CAS No. 1810700-89-0

  • Cat. No. CS-0380733
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2,4-Dichloroimidazo[2,1-f][1,2,4]triazine|CS-0380733

Structure of 1810700-89-0

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General Information

  • CAS No. 1810700-89-0
  • Cat. No. CS-0380733
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, stored under nitrogen, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₂Cl₂N₄
  • Molecular Weight 189.00
  • Synonym(s) None
  • SMILES ClC1=NC(Cl)=NN2C1=NC=C2

Description

2,4-Dichloroimidazo[2,1-f][1,2,4]triazine is a heterocyclic scaffold featuring two chlorine substituents at electron-rich positions, enabling robust coupling in transition-metal-catalyzed cross-coupling reactions. This bench-stable, moisture-tolerant core integrates readily into complex molecular architectures, offering high reactivity and selectivity in pharmaceutical and agrochemical synthesis.

Application

2,4-Dichloroimidazo[2,1-f][1,2,4]triazine serves as a versatile building block for constructing nitrogen-rich heterocyclic scaffolds. Its dichloro substitution enables selective nucleophilic displacement reactions, facilitating the installation of diverse side chains in medicinal chemistry and agrochemical synthesis. The compound exhibits good bench stability and compatibility with standard coupling protocols, making it well-suited for modular library development and process-scale applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   43.08
  • LogP   1.4311
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   0

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