Tos-O-C4-NH-Boc

Name: Tos-O-C4-NH-Boc
Brand: ChemScene
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CAS No. 180851-50-7
Cat. No. CS-0146735
Purity≥97%
MDL No.MFCD18839142

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FedEx Limited Quantities Ground	$0.00
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
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General Information

CAS No. 180851-50-7
Cat. No. CS-0146735
Purity ≥97%
MDL No. MFCD18839142
Storage -20°C, sealed storage, away from moisture
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₆H₂₅NO₅S
Molecular Weight 343.44
Synonym(s) None
SMILES O=C(OC(C)(C)C)NCCCCOS(=O)(C1=CC=C(C)C=C1)=O

Description

Tos-O-C4-NH-Boc features a tosyl-protected aliphatic amine tethered to a butyl linker, enabling stable conjugation in peptide synthesis. This derivative delivers precise functionalization with orthogonal deprotection compatibility, facilitating efficient assembly of complex biomolecules under standard conditions.

Application

Tos-O-C4-NH-Boc serves as a versatile building block for the synthesis of functionalized heterocycles and peptide-like scaffolds. The tosyl-protected amine enables orthogonal functionalization, while the Boc group offers stable protection under standard reaction conditions. Its bench-stable nature and compatibility with diverse coupling protocols facilitate efficient access to complex molecular architectures in medicinal chemistry and process development workflows.

Safety Information

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Signal Word : N/A	UN#: N/A
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Hazard Statements : N/A
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Computational Chemistry Data

TPSA 81.7
LogP 3.00522
H_Acceptors 5
H_Donors 1
Rotatable_Bonds 7

Other Classifications

Life Science Linker Non-PEG linker

Key Words

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Tos-O-C4-NH-Boc

CAS No. 180851-50-7

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