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CS-W001157 4
Total: USD 88.00

(2-Bromopyridin-3-yl)boronic acid

  • CAS No. 452972-08-6

  • Cat. No. CS-W015532
  • Purity≥97%
  • MDL No.MFCD04113805

*For research and further manufacturing use only, not for direct human use.

(2-Bromopyridin-3-yl)boronic acid|CS-W015532

Structure of 452972-08-6

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General Information

  • CAS No. 452972-08-6
  • Cat. No. CS-W015532
  • Purity ≥97%
  • MDL No. MFCD04113805
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₅BBrNO₂
  • Molecular Weight 201.81
  • Synonym(s) boronic acid, B-(2-bromo-3-pyridinyl)-
  • SMILES OB(C1=CC=CN=C1Br)O

Description

2-Bromoethyl phenyl sulfide, is used to make other chemicals as well as pharmaceutical intermediate. It is also used as a application intermediate.

Application

(2-Bromopyridin-3-yl)boronic acid serves as a versatile building block in cross-coupling reactions, enabling efficient C–C bond formation under palladium catalysis. Its bromine and boronic acid functionalities offer orthogonal reactivity for sequential functionalization. The compound exhibits good bench stability, facilitates straightforward purification, and is compatible with a range of standard coupling protocols, making it a practical choice for constructing pyridine-based scaffolds in medicinal chemistry and materials science.

Synthesis

  • Route1
    • 2,3-Dibromopyridine|CS-D1702
      13534-89-9
    • ~58%
    • In-stock
      (2-Bromopyridin-3-yl)boronic acid|CS-W015532
      452972-08-6

    References

    • Bouillon, Alexandre; Lancelot, Jean-Charles; Collot, Valerie; Bovy, Philippe R.; Rault, Sylvain Tetrahedron, 2002 , vol. 58, # 17 p. 3323 - 3328
  • Route2
    • null|null
      109-04-6
    • ~44%
    • In-stock
      (2-Bromopyridin-3-yl)boronic acid|CS-W015532
      452972-08-6

    References

    • Bouillon, Alexandre; Lancelot, Jean-Charles; Collot, Valerie; Bovy, Philippe R.; Rault, Sylvain Tetrahedron, 2002 , vol. 58, # 17 p. 3323 - 3328
  • Route3

    References

    • Bouillon, Alexandre; Lancelot, Jean-Charles; Collot, Valerie; Bovy, Philippe R.; Rault, Sylvain Tetrahedron, 2002 , vol. 58, # 17 p. 3323 - 3328

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   53.35
  • LogP   -0.4761
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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